Combining Pairwise Sequence Similarity and Support Vector Machines for Detecting Remote Protein Evolutionary and Structural Relationships.
Li LiaoWilliam Stafford NoblePublished in: J. Comput. Biol. (2003)
Keyphrases
- sequence similarity
- protein structure prediction
- pairwise
- support vector
- computational methods
- learning machines
- loss function
- large margin classifiers
- protein structure
- genome scale
- protein sequences
- multi class
- secondary structure
- protein folding
- graph theory
- sequence alignment
- amino acids
- coarse grained
- feature selection
- similarity measure
- statistical significance
- markov random field
- dna binding
- multiple sequence alignment
- support vector machine
- multiple sequence alignments