Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington's disease mice.
Lucile MégretSatish Sasidharan NairJulia DancourtJeff AaronsonJim RosinskiChristian NériPublished in: BMC Bioinform. (2020)
Keyphrases
- shape analysis
- feature selection
- gene expression
- gene function
- computational methods
- shape representation
- gene ontology
- microarray data analysis
- gene sets
- shape descriptors
- regulatory networks
- microarray data
- medical imaging
- microarray
- image analysis and pattern recognition
- gene expression data
- secondary structure
- post transcriptional
- genome wide
- binding sites
- high dimensionality
- text classification
- shape space
- machine learning
- mutual information
- microarray datasets
- support vector
- gene regulation
- high throughput
- feature extraction
- high dimensional
- image registration
- dimensionality reduction
- medical images
- high dimensional data