Transcription factor regulatory modules provide the molecular mechanisms for functional redundancy observed among transcription factors in yeast.
Tzu-Hsien YangPublished in: BMC Bioinform. (2019)
Keyphrases
- transcription factors
- binding sites
- gene expression
- microarray
- genome wide
- component analysis
- dna binding
- dna sequences
- computational biology
- co occurrence
- regulatory networks
- gene regulation
- systems biology
- saccharomyces cerevisiae
- high throughput
- cell cycle
- biological processes
- biomedical literature
- transcriptional regulation
- microarray data
- highly correlated
- gene expression data
- motif discovery
- protein protein interactions
- cis regulatory
- gene ontology
- gene sets
- transcription factor binding sites
- sequence data
- experimental conditions
- blind source separation
- signaling pathways
- statistical significance