Ligand Clouds around Protein Clouds: A Scenario of Ligand Binding with Intrinsically Disordered Proteins.
Fan JinChen YuLuhua LaiZhirong LiuPublished in: PLoS Comput. Biol. (2013)
Keyphrases
- protein protein
- drug design
- protein sequences
- protein function
- protein structure
- protein protein interactions
- amino acid sequences
- amino acids
- computational methods
- protein structure prediction
- dna binding
- binding sites
- experimentally determined
- predicting protein
- high throughput
- interaction networks
- virtual screening
- intrinsically disordered
- drug discovery
- molecular biology
- secondary structure
- protein complexes
- protein interaction data
- computational biology
- protein interaction
- hiv protease
- subcellular localization
- gene ontology
- computational approaches
- protein interaction networks
- biomedical literature
- transcription factor binding sites
- transcription factors
- sequence analysis
- physicochemical properties
- graph theory