Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6, 700 cancer genomes.
Chuang LiuJunfei ZhaoWeiqiang LuYao DaiJennifer HockingsYadi ZhouRuth NussinovCharis EngFeixiong ChengPublished in: PLoS Comput. Biol. (2020)
Keyphrases
- network analysis
- human genome
- cancer patients
- social network analysis
- copy number
- information networks
- text mining
- network structure
- complex networks
- breast cancer
- link prediction
- dna sequences
- genetic algorithm
- genome wide
- community detection
- genomic data
- protein protein interactions
- prostate cancer
- dna copy number
- graph clustering
- community structure
- sequence data
- clinical trials
- real world networks
- graph theory
- learning process
- breast cancer patients
- biological networks
- information retrieval
- centrality measures
- dynamic networks
- community discovery
- social networks