Prioritizing predictive biomarkers for gene essentiality in cancer cells with mRNA expression data and DNA copy number profile.
Yuanfang GuanTingyang LiHongjiu ZhangFan ZhuGilbert S. OmennPublished in: Bioinform. (2018)
Keyphrases
- cancer cells
- dna copy number
- genome wide
- gene function
- high throughput
- mass spectrometry
- expression profiles
- gene sets
- gene expression profiles
- biologically meaningful
- microarray data
- microarray
- splice site
- regulatory networks
- quantitative analysis
- lung cancer
- early detection
- gene prediction
- gene regulatory networks
- breast cancer
- high rate
- gene expression
- human genome
- microscopy images
- single nucleotide polymorphisms
- signaling pathways
- protein protein interactions
- transcription factors
- gene ontology
- gene expression data
- gene selection
- alternative splicing
- cell cycle
- gene networks
- statistical significance
- molecular biology
- copy number
- binding sites
- image processing