High-dimension to high-dimension screening for detecting genome-wide epigenetic and noncoding RNA regulators of gene expression.
Hongjie KeZhao RenJianfei QiShuo ChenGeorge C. TsengZhenyao YeTianzhou MaPublished in: Bioinform. (2022)
Keyphrases
- high dimension
- genome wide
- transcription factors
- high throughput
- gene expression
- microarray
- dna binding
- feature space
- high dimensional
- regulatory networks
- feature selection
- gene regulation
- differential expression
- human genome
- transcriptional regulation
- expression patterns
- systems biology
- genome scale
- gene expression data
- high dimensional data
- microarray data
- cell cycle
- biological processes
- saccharomyces cerevisiae
- genomic data
- biological data
- dimensionality reduction
- binding sites
- gene expression profiles
- support vector machine
- regulatory elements
- experimental conditions
- biological networks
- rna seq
- high dimensionality
- transcription factor binding sites