DeepFNN-DTBA: prediction of drug-target binding affinity via feed-forward neural network on drug-protein sequences.
Moolchand SharmaSuman DeswalPublished in: J. Electronic Imaging (2022)
Keyphrases
- protein sequences
- feed forward neural networks
- protein secondary structure
- physico chemical
- protein classification
- protein structure prediction
- computational biology
- multiple sequence alignments
- back propagation
- protein secondary structure prediction
- neural network
- amino acids
- protein structure
- secondary structure
- multi layer
- experimentally determined
- prediction accuracy
- artificial neural networks
- biological sequences
- feed forward
- protein function
- remote homology detection
- hidden layer
- pairwise
- prediction model
- sequence analysis
- basis functions
- coarse grained
- activation function
- protein structural
- fuzzy inference system
- amino acid sequences
- hiv protease
- multiple alignment
- psi blast
- fuzzy sets
- drug discovery
- control system
- subcellular localization
- multiple sequence alignment
- feature space
- learning algorithm
- data mining