In silico saturation mutagenesis and docking screening for the analysis of protein-ligand interaction: the Endothelial Protein C Receptor case study.
Federica ChiapporiPasqualina D'UrsiIvan MerelliLuciano MilanesiErmanna RovidaPublished in: BMC Bioinform. (2009)
Keyphrases
- drug discovery
- case study
- virtual screening
- protein sequences
- amino acids
- computational methods
- image analysis
- early stage
- real world
- protein interaction
- protein structure prediction
- protein protein
- protein interaction data
- computer simulation
- high throughput
- statistical analysis
- protein structure
- software development
- data sources
- mass spectrometry data
- subcellular localization
- wet lab