Characterizing therapeutic signatures of transcription factors in cancer by incorporating profiles in compound treated cells.
Jinmyung JungPublished in: Bioinform. (2021)
Keyphrases
- transcription factors
- binding sites
- cancer cells
- microarray
- gene expression
- differential expression
- dna binding
- cancer patients
- dna sequences
- gene selection
- component analysis
- genome wide
- gene expression profiles
- gene regulation
- systems biology
- regulatory networks
- high throughput
- computational biology
- transcription factor binding sites
- breast cancer
- cancer diagnosis
- motif discovery
- co occurrence
- biomedical literature
- highly correlated
- early detection
- cancer classification
- statistical significance
- microarray data
- biological processes
- gene sets
- cell cycle
- lung cancer
- protein sequences
- gene expression data
- cis regulatory
- machine learning