Incorporating interaction networks into the determination of functionally related hit genes in genomic experiments with Markov random fields.
Sean RobinsonJaakko NevalainenGuillaume PinnaAnna CampalansJ. Pablo RadicellaLaurent GuyonPublished in: Bioinform. (2017)
Keyphrases
- markov random field
- interaction networks
- high throughput
- systems biology
- higher order
- graph cuts
- gene regulatory networks
- belief propagation
- maximum a posteriori
- parameter estimation
- biological processes
- energy function
- image segmentation
- markov networks
- pairwise
- saccharomyces cerevisiae
- conditional random fields
- biological knowledge
- protein protein interaction networks
- microarray
- gene expression data
- gene expression
- genomic data
- protein function
- message passing
- genome wide
- protein protein interactions
- sequence data
- biological data
- similarity measure