William R. Holmes

Publication Activity (10 Years)

Years Active: 2006-2021
Publications (10 Years): 5

Top Topics

Gene Expression Data Analysis

Simple Examples

Computational Models

Gene Expression

Top Venues

PLoS Comput. Biol.

Publications

Zixuan Cang, Yangyang Wang, Qixuan Wang, Ken W. Y. Cho, William R. Holmes, Qing Nie
A multiscale model via single-cell transcriptomics reveals robust patterning mechanisms during early mammalian embryo development. PLoS Comput. Biol. 17 (3) (2021)
Ximing Li, William R. Holmes
Biophysical attributes that affect CaMKII activation deduced with a novel spatial stochastic simulation approach. PLoS Comput. Biol. 14 (2) (2018)
William R. Holmes, Jinseok Park, Andre Levchenko, Leah Edelstein-Keshet
A mathematical model coupling polarity signaling to cell adhesion explains diverse cell migration patterns. PLoS Comput. Biol. 13 (5) (2017)
William R. Holmes, Nabora de Mochel, Qixuan Wang, Huijing Du, Tao Peng, Michael Chiang, Olivier Cinquin, Ken Cho, Qing Nie
Gene Expression Noise Enhances Robust Organization of the Early Mammalian Blastocyst. PLoS Comput. Biol. 13 (1) (2017)
Qixuan Wang, William R. Holmes, Julian Sosnik, Thomas Schilling, Qing Nie
Cell Sorting and Noise-Induced Cell Plasticity Coordinate to Sharpen Boundaries between Gene Expression Domains. PLoS Comput. Biol. 13 (1) (2017)
Huijing Du, Qing Nie, William R. Holmes
The Interplay between Wnt Mediated Expansion and Negative Regulation of Growth Promotes Robust Intestinal Crypt Structure and Homeostasis. PLoS Comput. Biol. 11 (8) (2015)
William R. Holmes, Leah Edelstein-Keshet
A Comparison of Computational Models for Eukaryotic Cell Shape and Motility. PLoS Comput. Biol. 8 (12) (2012)
William R. Holmes, Benjamin Lin, Andre Levchenko, Leah Edelstein-Keshet
Modelling Cell Polarization Driven by Synthetic Spatially Graded Rac Activation. PLoS Comput. Biol. 8 (6) (2012)
José Ambros-Ingerson, Lawrence M. Grover, William R. Holmes
A Classification Method to Distinguish Cell-Specific Responses Elicited by Current Pulses in Hippocampal CA1 Pyramidal Cells. Neural Comput. 20 (6) (2008)
William R. Holmes, José Ambros-Ingerson, Lawrence M. Grover
Fitting experimental data to models that use morphological data from public databases. J. Comput. Neurosci. 20 (3) (2006)