Philip M. Dean

Publication Activity (10 Years)

Years Active: 1992-2007
Publications (10 Years): 0

Publications

Nikolay P. Todorov, Ian L. Alberts, Iwan J. P. de Esch, Philip M. Dean
QUASI: A Novel Method for Simultaneous Superposition of Multiple Flexible Ligands and Virtual Screening Using Partial Similarity. J. Chem. Inf. Model. 47 (3) (2007)
Stuart Firth-Clark, Nikolay P. Todorov, Ian L. Alberts, Anthony Williams, Timothy James, Philip M. Dean
Exhaustive de novo Design of Low-Molecular-Weight Fragments Against the ATP-Binding Site of DNA-Gyrase. J. Chem. Inf. Model. 46 (3) (2006)
Martin Stahl, Nikolay P. Todorov, Timothy James, Harald Mauser, Hans-Joachim Böhm, Philip M. Dean
A validation study on the practical use of automated de novo design. J. Comput. Aided Mol. Des. 16 (7) (2002)
J. E. J. Mills, Iwan J. P. de Esch, Tim D. J. Perkins, Philip M. Dean
Slate: A method for the superposition of flexible ligands. J. Comput. Aided Mol. Des. 15 (1) (2001)
S. L. Garland, Philip M. Dean
Design criteria for molecular mimics of fragments of the beta-turn. 2. C-alpha-C-beta bond vector analysis. J. Comput. Aided Mol. Des. 13 (5) (1999)
S. L. Garland, Philip M. Dean
Design criteria for molecular mimics of fragments of the beta-turn. 1. C-alpha atom analysis. J. Comput. Aided Mol. Des. 13 (5) (1999)
Nikolay P. Todorov, Philip M. Dean
A branch-and-bound method for optimal atom-type assignment in de novo ligand design. J. Comput. Aided Mol. Des. 12 (4) (1998)
J. E. J. Mills, Tim D. J. Perkins, Philip M. Dean
An automated method for predicting the positions of hydrogen-bonding atoms in binding sites. J. Comput. Aided Mol. Des. 11 (3) (1997)
Nikolay P. Todorov, Philip M. Dean
Evaluation of a method for controlling molecular scaffold diversity in de novo ligand design. J. Comput. Aided Mol. Des. 11 (2) (1997)
J. E. J. Mills, Philip M. Dean
Three-dimensional hydrogen-bond geometry and probability information from a crystal survey. J. Comput. Aided Mol. Des. 10 (6) (1996)
Tim D. J. Perkins, J. E. J. Mills, Philip M. Dean
Molecular surface-volume and property matching to superpose flexible dissimilar molecules. J. Comput. Aided Mol. Des. 9 (6) (1995)
P.-L. Chau, Philip M. Dean
Electrostatic complementarity between proteins and ligands. 2. Ligand moieties. J. Comput. Aided Mol. Des. 8 (5) (1994)
P.-L. Chau, Philip M. Dean
Electrostatic complementarity between proteins and ligands. 1. Charge disposition, dielectric and interface effects. J. Comput. Aided Mol. Des. 8 (5) (1994)
P.-L. Chau, Philip M. Dean
Electrostatic complementarity between proteins and ligands. 3. Structural basis. J. Comput. Aided Mol. Des. 8 (5) (1994)
Tim D. J. Perkins, Philip M. Dean
An exploration of a novel strategy for superposing several flexible molecules. J. Comput. Aided Mol. Des. 7 (2) (1993)
P.-L. Chau, Philip M. Dean
Automated site-directed drug design: The generation of a basic set of fragments to be used for automated structure assembly. J. Comput. Aided Mol. Des. 6 (4) (1992)
P.-L. Chau, Philip M. Dean
Automated site-directed drug design: An assessment of the transferability of atomic residual charges (CNDO) for molecular fragments. J. Comput. Aided Mol. Des. 6 (4) (1992)
P.-L. Chau, Philip M. Dean
Automated site-directed drug design: Searches of the Cambridge Structural Database for bond lengths in molecular fragments to be used for automated structure assembly. J. Comput. Aided Mol. Des. 6 (4) (1992)