Michael Houghton

Publication Activity (10 Years)

Years Active: 1980-2020
Publications (10 Years): 1

Top Topics

Essential Proteins

Quantitative Structure Activity

Molecular Dynamics

Top Venues

J. Chem. Inf. Model.

Int. J. Comput. Model. Algorithms Medicine

Publications

Holly Freedman, Juthika Kundu, Egor Petrovitch Tchesnokov, John Lok Man Law, James A. Nieman, Raymond F. Schinazi, D. Lorne Tyrrell, Matthias Gotte, Michael Houghton
Application of Molecular Dynamics Simulations to the Design of Nucleotide Inhibitors Binding to Norovirus Polymerase. J. Chem. Inf. Model. 60 (12) (2020)
Khaled H. Barakat, Anwar Anwar-Mohamed, Jack A. Tuszynski, Morris J. Robins, D. Lorne Tyrrell, Michael Houghton
A Refined Model of the HCV NS5A Protein Bound to Daclatasvir Explains Drug-Resistant Mutations and Activity against Divergent Genotypes. J. Chem. Inf. Model. 55 (2) (2015)
Khaled H. Barakat, Michael Houghton, D. Lorne Tyrrell, Jack A. Tuszynski
Rational Drug Design: One Target, Many Paths to It. Int. J. Comput. Model. Algorithms Medicine 4 (1) (2014)
Khaled H. Barakat, John Law, Alessio Prunotto, Wendy C. Magee, David H. Evans, D. Lorne Tyrrell, Jack A. Tuszynski, Michael Houghton
Detailed Computational Study of the Active Site of the Hepatitis C Viral RNA Polymerase to Aid Novel Drug Design. J. Chem. Inf. Model. 53 (11) (2013)
Jang H. Han, Michael Houghton
Group specific sequences and conserved secondary structures at the 3' end of HCV genome and its implication for viral replication. Nucleic Acids Res. 20 (13) (1992)
Michael Houghton, M. A. Easton, A. G. Stewart, J. C. Smith, S. M. Doel, G. H. Catlin, H. M. Lewis, T. P. Patel, J. S. Emtage, N. H. Carey, Andrew C. G. Porter
The complete amino acid sequence of human fibroblast interferon as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptase. Nucleic Acids Res. 8 (13) (1980)