Bryan L. Roth

Publication Activity (10 Years)

Years Active: 2009-2023
Publications (10 Years): 2

Top Topics

Virtual Screening

Weakly Supervised

Ground Penetrating Radar

Top Venues

J. Chem. Inf. Model.

Publications

Leslie Salas-Estrada, Davide Provasi, Xing Qiu, Husnu Ümit Kaniskan, Xi-Ping Huang, Jeffrey F. Diberto, João Marcelo Lamim Ribeiro, Jian Jin, Bryan L. Roth, Marta Filizola
De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep-Learning Framework. J. Chem. Inf. Model. 63 (16) (2023)
Aashish Manglik, Henry Lin, Dipendra K. Aryal, John D. McCorvy, Daniela Dengler, Gregory Corder, Anat Levit, Ralf C. Kling, Viachaslau Bernat, Harald Hübner, Xi-Ping Huang, Maria F. Sassano, Patrick M. Giguère, Stefan Löber, Da Duan, Grégory Scherrer, Brian K. Kobilka, Peter Gmeiner, Bryan L. Roth, Brian K. Shoichet
Structure-based discovery of opioid analgesics with reduced side effects. Nat. 537 (7619) (2016)
Xi-Ping Huang, Joel Karpiak, Wesley K. Kroeze, Hu Zhu, Xin Chen, Sheryl S. Moy, Kara A. Saddoris, Viktoriya D. Nikolova, Martilias S. Farrell, Sheng Wang, Thomas J. Mangano, Deepak A. Deshpande, Alice Jiang, Raymond B. Penn, Jian Jin, Beverly H. Koller, Terry Kenakin, Brian K. Shoichet, Bryan L. Roth
Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nat. 527 (7579) (2015)
Denis Fourches, Maria F. Sassano, Bryan L. Roth, Alexander Tropsha
HTS navigator: freely accessible cheminformatics software for analyzing high-throughput screening data. Bioinform. 30 (4) (2014)
Man Luo, Xiang Simon Wang, Bryan L. Roth, Alexander Golbraikh, Alexander Tropsha
Ligands. J. Chem. Inf. Model. 54 (2) (2014)
Hao Tang, Xiang S. Wang, Xi-Ping Huang, Bryan L. Roth, Kyle V. Butler, Alan P. Kozikowski, Mira Jung, Alexander Tropsha
Novel Inhibitors of Human Histone Deacetylase (HDAC) Identified by QSAR Modeling of Known Inhibitors, Virtual Screening, and Experimental Validation. J. Chem. Inf. Model. 49 (2) (2009)