Aleksander S. Popel

Publication Activity (10 Years)

Years Active: 1999-2024
Publications (10 Years): 11

Top Topics

Text Based Image Retrieval

Multiple Instance

Computational Models

Outcome Prediction

Top Venues

PLoS Comput. Biol.

Briefings Bioinform.

Publications

Theinmozhi Arulraj, Hanwen Wang, Alberto Ippolito, Shuming Zhang, Elana J. Fertig, Aleksander S. Popel
Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology. Briefings Bioinform. 25 (3) (2024)
Hanwen Wang, Theinmozhi Arulraj, Alberto Ippolito, Aleksander S. Popel
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling. npj Digit. Medicine 7 (1) (2024)
Zhenzhen Wang, Carla Saoud, Sintawat Wangsiricharoen, Aaron W. James, Aleksander S. Popel, Jeremias Sulam
Label Cleaning Multiple Instance Learning: Refining Coarse Annotations on Single Whole-Slide Images. IEEE Trans. Medical Imaging 41 (12) (2022)
Alvaro Ruiz-Martinez, Chang Gong, Hanwen Wang, Richard J. Sové, Haoyang Mi, Holly Kimko, Aleksander S. Popel
Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model. PLoS Comput. Biol. 18 (7) (2022)
Zhenzhen Wang, Aleksander S. Popel, Jeremias Sulam
Label Cleaning Multiple Instance Learning: Refining Coarse Annotations on Single Whole-Slide Images. CoRR (2021)
Chen Zhao, Adam C. Mirando, Richard J. Sové, Thalyta X. Medeiros, Brian H. Annex, Aleksander S. Popel
A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology. PLoS Comput. Biol. 15 (11) (2019)
Chen Zhao, Jeffrey S. Isenberg, Aleksander S. Popel
Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model. PLoS Comput. Biol. 13 (1) (2017)
Kerri-Ann Norton, Travis Wallace, Niranjan B. Pandey, Aleksander S. Popel
An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia. BMC Syst. Biol. 11 (1) (2017)
Hojjat Bazzazi, Aleksander S. Popel
Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells. PLoS Comput. Biol. 13 (2) (2017)
Polyxeni Gkontra, Magdalena M. Zak, Kerri-Ann Norton, Andrés Santos, Aleksander S. Popel, Alicia G. Arroyo
A 3D Fractal-Based Approach towards Understanding Changes in the Infarcted Heart Microvasculature. MICCAI (3) (2015)
Chen Zhao, Aleksander S. Popel
Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer. PLoS Comput. Biol. 11 (11) (2015)
Prakash Vempati, Aleksander S. Popel, Feilim Mac Gabhann
Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis. BMC Syst. Biol. 5 (2011)
Stacey D. Finley, Marianne O. Engel-Stefanini, Princess I. Imoukhuede, Aleksander S. Popel
Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies. BMC Syst. Biol. 5 (2011)
Amina A. Qutub, Gang Liu, Prakash Vempati, Aleksander S. Popel
Integration of Angiogenesis Modules at Multiple Scales: From Molecular to Tissue. Pacific Symposium on Biocomputing (2009)
Amina A. Qutub, Aleksander S. Popel
Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting. BMC Syst. Biol. 3 (2009)
Marianne O. Stefanini, Florence T. H. Wu, Feilim Mac Gabhann, Aleksander S. Popel
The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling. PLoS Comput. Biol. 5 (12) (2009)
Marianne O. Stefanini, Florence T. H. Wu, Feilim Mac Gabhann, Aleksander S. Popel
A compartment model of VEGF distribution in blood, healthy and diseased tissues. BMC Syst. Biol. 2 (2008)
Feilim Mac Gabhann, James W. Ji, Aleksander S. Popel
Computational Model of Vascular Endothelial Growth Factor Spatial Distribution in Muscle and Pro-Angiogenic Cell Therapy. PLoS Comput. Biol. 2 (9) (2006)
Feilim Mac Gabhann, Aleksander S. Popel
Targeting Neuropilin-1 to Inhibit VEGF Signaling in Cancer: Comparison of Therapeutic Approaches. PLoS Comput. Biol. 2 (12) (2006)
Kreg G. Gruben, Henry R. Halperin, Aleksander S. Popel, Joshua E. Tsitlik
Canine sternal force-displacement relationship during cardiopulmonary resuscitation. IEEE Trans. Biomed. Eng. 46 (7) (1999)